Abstract
Estrogens both alone and in combination with progestagens, gonadotrophins, gonadotrophin-releasing factor, corticosteroids, and corticotrophin antagonise the head-twitch response produced by 5-hydroxytryptophan in mice. In contrast, a potentiation was seen following thyroid hormones, thyrotrophin, and thyrotrophin-releasing hormone. Pretreatment with androgens had no significant effect. Possible mechanisms for these interactions are discussed.
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Brotherton, C.S., Doggett, N.S. Modification of the 5-hydroxytryptophan-induced head-twitch response by exogenous endocrine agents. Psychopharmacology 58, 145–151 (1978). https://doi.org/10.1007/BF00426897
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DOI: https://doi.org/10.1007/BF00426897