Abstract
During the last century, clues that hormones might affect behavior arose both from laboratory experiments and in the clinic. Frank Beach, working with animals at the University of California, Berkeley, demonstrated the activation of male sexual behavior by testosterone injections, as well as the facilitation of female sexual behavior by treatments with estrogens and progesterone. In the clinic, it was clear that hyperthyroid patients could be nervous and irritable, while hypothyroid patients would be sluggish and dull. As well, eunuchs (lacking testosterone from the testes) had no libido, and thus, clinical experience went hand in hand with Beach’s experimental demonstration.
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References
Choleris E, Gustafsson JA, Korach KS, Muglia LJ, Pfaff DW, Ogawa S (2003) An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice. Proc Natl Acad Sci U S A 100(10):6192–6197
Donaldson ZR, Young LJ (2008) Oxytocin, vasopressin, and the neurogenetics of sociality. Science 322(5903):900–904
Kow LM, Montgomery MO, Pfaff DW (1979) Triggering of lordosis reflex in female rats with somatosensory stimulation: quantitative determination of stimulus parameters. J Neurophysiol 42(1 Pt 1):195–202
Morton GJ, Schwartz MW (2001) The NPY/AgRP neuron and energy homeostasis. Int J Obes Relat Metab Disord 25(Suppl 5):S56–S62
Pfaff DW, Phillips MI, Rubin RT (2004) Principles of hormone/behavior relations. Elsevier/Academic, Amsterdam
Romeo RD, Waters EM, McEwen BS (2004) Steroid-induced hippocampal synaptic plasticity: sex differences and similarities. Neuron Glia Biol 1(3):219–229
Sandi C (2004) Stress, cognitive impairment and cell adhesion molecules. Nat Rev Neurosci 5(12):917–930
Schwartz MW (2001) Brain pathways controlling food intake and body weight. Exp Biol Med (Maywood) 226(11):978–981
Woolley CS, McEwen BS (1992) Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat. J Neurosci 12(7):2549–2554; Erratum in: J Neurosci 12(10):following table of contents
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Litvin, Y., Pfaff, D.W. (2016). Hormone Effects on Behavior. In: Pfaff, D., Volkow, N. (eds) Neuroscience in the 21st Century. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3474-4_59
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DOI: https://doi.org/10.1007/978-1-4939-3474-4_59
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