Abstract
Male albino guinea pigs aged 4–10 weeks were challenged with 0.1, 0.2, and 0.4 mg/kg apomorphine. Mean stereotypy scores rose significantly as a function of age. Stereotypy scores were better correlated with age than with body weight, suggesting that CNS maturation, rather than weight-related factors, was responsible. Although age and body weight were correlated, there was enough variability to make body weight an unreliable indicator of age.
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Carlson, K.R., Almasi, J. Sensitivity to apomorphine in the guinea pig as a function of age and body weight. Psychopharmacology 57, 279–282 (1978). https://doi.org/10.1007/BF00426751
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DOI: https://doi.org/10.1007/BF00426751