Abstract
Rats were tested in a Lashley III maze, the floor of which was heated. The animals had to learn to negotiate it in order to gain access to the unheated goal box.
In the early period of training the animals were able to find the goal box rapidly and without error. Their performance then deteriorated, in a particular way which strongly evoked a conflict behavior.
This deterioration in performance was progressively reduced by oxazepam administration (8 mg/kg/day).
Similar content being viewed by others
References
Geller, I.: Relative potencies of benzodiazepines as measured by their effects on conflict behavior. Arch. int. Pharmacodyn. 149, 243–247 (1964).
Lashley, K. F.: Brain mechanisms and Intelligence, p. 31. Chicago: University of Chicago Press 1929.
Margules, D. L., Stein, L.: Increase of “antianxiety” activity and tolerance of behavioural depression during chronic administration of oxazepam. Psychopharmacologia (Berl.) 13, 74–80 (1968).
Miller, N. E., Barry, H.: Motivational effects of drugs: methods which illustrate some general problems in psychopharmacology. Psychopharmacologia (Berl.) 1, 169–199. (1960).
Palosi, E., Szporny, L.: New, simple method for the informative investigation of sedatives. Psychopharmacologia (Berl.) 12, 44–49 (1967).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Soubrié, P., Schoonhoed, L., Simon, P. et al. Conflict behavior in a heated-floor maze: Effects of oxazepam. Psychopharmacologia 26, 317–320 (1972). https://doi.org/10.1007/BF00422708
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00422708