Summary
Thirteen patients, eleven of whom had asthma, were treated with ordinary therapeutic dosages of Celeston Chronodose (a mixture of disodium phosphate and of acetate of betamethasone) or Depo-Medrol (6-methylprednisolone acetate). Duration of the effect of one single intramuscular injection lasted from 1–6 days, if judged by clinical improvement and by suppression of plasma 11-OHCS and by the blood eosinophil count. It was concluded that parenteral administration of depotcorticosteroids per mg does not prolong the effect of the corticosteroids as compared with the oral route.
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Frey, H., Norman, N. Duration of action of depot-corticosteroids. Pharmacol. Clin. 2, 109–112 (1970). https://doi.org/10.1007/BF00420716
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DOI: https://doi.org/10.1007/BF00420716