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The monocistronic nature of ribosomal protein genes in yeast

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Summary

The synthesis of thirty five ribosomal proteins has been studied in Saccharomyces cerevisiae using a temperature sensitive mutant blocked in the initiation of polypeptides. The synthesis of all the ribosomal proteins was nearly equally affected by the block. This absence of polarity, together with previous genetic and biochemical data, indicates that eukaryotic ribosomal proteins are coded by monocistronic mRNAs.

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Author notes

  1. Charles Gorenstein

    Present address: School of Medicine, Department of Pharmacology, and Experimental Therapeutics, The Johns Hopkins University, 725 North Wolfe Street, 21205, Baltimore, Maryland, USA

Authors and Affiliations

  1. Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, 10461, Bronx, New York, USA

    Charles Gorenstein & Jonathan R. Warner

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  1. Charles Gorenstein
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  2. Jonathan R. Warner
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Gorenstein, C., Warner, J.R. The monocistronic nature of ribosomal protein genes in yeast. Curr Genet 1, 9–12 (1979). https://doi.org/10.1007/BF00413302

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  • DOI: https://doi.org/10.1007/BF00413302

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