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Cathepsin B and collagenolytic cathepsin in the aqueous humor of patients with Behçet's disease

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Summary

Cathepsin B and collagenolytic cathepsin activities were studied biochemically in human aqueous humor. The enzyme activities were found to be significantly high in the aqueous humor of the patients with Behçet's disease, but not detectable in those with senile cataract, retinoblastoma, and maxillar carcinoma.

These data suggest that cathepsin B and collagenolytic cathepsin have a certain role in the inflammatory collagenolytic process of Behçet's disease.

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Authors and Affiliations

  1. Department of Ophthalmology School of Medicine, Tohoku University, 980, Sendai, Japan

    Seiji Hayasaka

  2. Department of Anatomy, School of Dentistry, Tohoku University, 980, Sendai, Japan

    Itsuko Hayasaka

Authors
  1. Seiji Hayasaka
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  2. Itsuko Hayasaka
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Hayasaka, S., Hayasaka, I. Cathepsin B and collagenolytic cathepsin in the aqueous humor of patients with Behçet's disease. Albrecht von Graefes Arch. Klin. Ophthalmol. 210, 103–107 (1979). https://doi.org/10.1007/BF00409996

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  • DOI: https://doi.org/10.1007/BF00409996

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