Summary
Rats conditioned on three values of FR, VR, FI and VI food reinforcement schedules were administered 1.0, 3.0 and 6.0 mg/kg I.P. of morphine or saline. Overall response rate varied with schedule, schedule value and morphine dose. The effect of morphine on overall rate varied with baseline saline rate generated by schedules, and the relative rate change also varied with the type of schedule.
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This research was supported in part by U.S.P.H.S. Research Grant MH-15349 to the University of Minnesota.
Copies of representative cumulative records at each morphine dose and schedule value can be obtained by writing to the senior author at Box 392 Mayo, University of Minnesota, Minneapolis, Minnesota.
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Thompson, T., Trombley, J., Luke, D. et al. Effects of morphine on behavior maintained by four simple food-reinforcement schedules. Psychopharmacologia 17, 182–192 (1970). https://doi.org/10.1007/BF00402708
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DOI: https://doi.org/10.1007/BF00402708