Abstract
The bacteriocin produced by Streptococcus faecalis var. zymogenes (E-1) is most active against Diplococcus pneumoniae and least against other strains of S. faecalis. Clostridium perfringens showed an intermediate susceptibility to the active principle. By utilizing the gas production of C. perfringens as an indicator of metabolic activity, a decrease in sensitivity to bacteriocin was demonstrated with aging of the culture. Non-viable pinpoint clostridial colonies frequently developed by exposure of C. perfringens to a 2 or 3 hr old E-1 broth culture. The action of E-1 as studied on C. perfringens appears to be bactericidal and only partially bacteriolytic. The extent of E-1 bactericidal activity on susceptible D. pneumoniae, C. perfringens, and S. faecalis was shown to be dependent upon bacteriocin concentration.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Basinger, S. F. and Jackson, R. W. 1968. Bacteriocin (Hemolysin) of Streptococcus zymogenes. — J. Bacteriol. 96: 1895–1902.
Bottone, E., Allerhand, J. and Pisano, M. A. 1971. Characteristics of a bacteriocin derived from Streptococcus faecalis var. zymogenes antagonistic to Diplococcus pneumoniae. — Appl. Microbiol. 22: 200–204.
Brock, T. D. and Davie, J. M. 1963. Probable identity of a Group D hemolysin with a bacteriocine. — J. Bacteriol. 86: 708–712.
Brock, T. D., Peacher, B. and Pierson, D. 1963. Survey of the bacteriocines of enterococci. — J. Bacteriol. 86: 702–707.
Dajani, A. S., Gray, E. D. and Wannamaker, L. W. 1970. Effect of a bactericidal substance from Staphylococcus aureus on group A streptococci. 1. Biochemical alterations. — Infec. Immun. 1: 485–490.
Davie, J. M. and Brock, T. D. 1966a. Action of streptolysin S, the group D hemolysin, and phospholipase C on whole cells and spheroplasts. — J. Bacteriol. 91: 595–599.
Davie, J. M. and Brock, T. D. 1966b. Effect of teichoic acid on resistance to the membranelytic agent of Streptococcus zymogenes. — J. Bacteriol. 92: 1623–1631.
Fredericq, P. 1957. Colicins. — Annu. Rev. Microbiol. 11: 7–22.
Granato, P. A. and Jackson, R. W. 1969. Bicomponent nature of a lysin from Streptococcus zymogenes. — J. Bacteriol. 100: 865–868.
Hamon, Y. et Peron, Y. 1963. Quelques remarques sur les bacteriocines produites par les microbes gram-positifs. — C. R. Acad. Sci. 257: 1191–1193.
Irwin, J. and Seeley, H. W.Jr. 1958. Titration and partial characterization of a soluble hemolysin of a group D streptococcus. — J. Bacteriol. 76: 29–35.
Ivanovics, G. 1962. Bacteriocins and bacteriocin-like substances. — Bacteriol. Rev. 26: 108–118.
Mahony, D. E. and Butler, M. E. 1971. Bacteriocins of Clostridium perfringens. 1. Isolation and preliminary studies. — Can. J. Microbiol. 17: 1–6.
Mahony, D. E., Butler, M. E. and Lewis, R. G. 1971. Bacteriocins of Clostridium perfringens. 2. Studies on mode of action. — Can. J. Microbiol. 17: 1435–1442.
Nomura, M. 1967. Colicins and related bacteriocins. — Annu. Rev. Microbiol. 21: 257–284.
Sanders, E. 1969. Bacterial interference. I. Its occurrence among the respiratory tract flora and characterization of inhibition of group A streptococci by viridans streptococci. —J. Infec. Dis. 120: 698–707.
Wicken, A. J., Elliott, S. D. and Baddiley, J. 1963. The identity of streptococcal group D antigen with teichoic acid. — J. Gen. Microbiol. 31: 231–239.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bottone, E., Allerhand, J. & Pisano, M.A. Effects of a bacteriocin produced by Streptococcus faecalis var. zymogenes (E-1) on susceptible microorganisms. Antonie van Leeuwenhoek 40, 385–392 (1974). https://doi.org/10.1007/BF00399350
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00399350