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Summary

The radioactive substance, 14C(U)d-Glucose, was indicated for the tracer study in the inner ear. It was injected intraperitonealy, intravenously, intra-arterialy, into the cerebrospinal and perilymphatic fluid directly. In the systemic injection, the radioactivity of perilymph showed the highest value. In cerebrospinal fluid, the radioactivity increased in a pattern similar to that of perilymph, and the decreases was more rapid than in perilymph. The radioactivity of endolymph was lowest among the above three. By the injection into the scala tympani, the radioactivity appeared immediately in cerebrospinal fluid, however, in the perilymph it was detectable only 1 min after the injection into the cerebrospinal space. The appearance of this radioactivity was suppressed by occlusion of the cochlear aqueduct.

Zusammenfassung

Radinaktive 14C(U)-d-Glucose wurde für eine Tracerstudie am Innenohr verwendet. Sie wurde intraperitoneal, intravenös, intraarteriell, in den Liquor Cerebro-spinalis and in die Perilymphe direkt injiziert. Bei Injektion in den Kreislauf zeigte die Radioaktivität der Perilymphe die höchsten Werte. Der Anstieg der Radioaktivität im Liquor Cerebro-spinalis erfolgte in einer ähnlichen Kurve wie der der Perilymphe, die Abnahme aber war schneller als in der Perilymphe. Die Radioaktivität der Endolymphe hatte die geringsten Werte der 3 Flüssigkeiten. Bei direkter Injektion in die Scala tympani erschien unmittelbar anschließend eine Radioaktivität im Liquor, dagegen war sic in der Perilymphe nach Injektion in den Cerebrospinalraum erst nach 1 min zu entdecken. Durch Verschluß des Aquäductus cochlae wurde das Aufscheinen einer Radioaktivität unterdrückt.

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Komaki, Y. Glucose transport in the inner ear. Arch. klin. exp. Ohr.-, Nas.- u. Kehlk.Heilk. 201, 258–269 (1972). https://doi.org/10.1007/BF00398009

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  • DOI: https://doi.org/10.1007/BF00398009

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