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Clinical enzymology for the assessment of organ damage: Interspecific differences

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Abstract

Enzyme activities in serum/plasma or urine are the most widely used markers of organ damage as well in human or animal clinics as in experimental toxicology. Significant interspecific differences can be observed for enzyme distribution in various species, extracellular metabolism, preanalytical and analytical conditions. Thus, to avoid any misinterpretation, all these criteria have to be documented and/or validated before use.

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Authors and Affiliations

  1. Département de Physiopathologie and Unité Associée INRA Physiopathologie et Toxicologie Expérimentales, Ecole Nationale Vétérinaire, Toulouse, France

    J. P. Braun, M. Aktas, H. Lefebvre, A. G. Rico & P. L. Toutain

Authors
  1. J. P. Braun
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  2. M. Aktas
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  3. H. Lefebvre
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  4. A. G. Rico
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  5. P. L. Toutain
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Originally presented at ECCP 93.

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Braun, J.P., Aktas, M., Lefebvre, H. et al. Clinical enzymology for the assessment of organ damage: Interspecific differences. Comparative Haematology International 3, 27–32 (1993). https://doi.org/10.1007/BF00394924

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