Summary
-
1.
Nuclear mutants lacking cytochrome c l spectrum have been isolated.
-
2.
The electron flow through the respiratory chain of the mutants is defect in the cytochrome bc 1-segment.
-
3.
Complementation analysis has yielded two major complementation groups.
-
4.
Tetrade analysis has established the two complementation groups as unlinked.
Similar content being viewed by others
Abbreviations
- pet− :
-
nuclear; respiratory deficient mutant
- rho− :
-
mitochondrial macro-deletion mutants without mitochondrial protein synthesis
- rho°:
-
mutant without mitochondrial DNA
- Nitrosoguanidine:
-
N-methyl-N′ nitro-N-nitrosoguanidine
References
Tzagoloff A, Macino G, Sebald W (1979) Annu Rev Biochem 49:419–441
Borst P, Grivell LA (1978) Cell 15:705–723
Haid A, Schweyen RJ, Bechman H, Kaudewitz F, Solioz M, Schatz G (1979) Eur J Biochem 94:451–464
Slonimski PP, Tzagoloff A (1976) Eur J Biochem 61:27–41
Dujardin G, Pajot P, Groudinsky O, Slonimski PP (1980) Mol Gen Genet 170:469–482
Ohashi A (unpublished results)
Sherman F, Stewart JW (1978) Biochemistry and Genetics of Yeast. Academic Press, pp 273–315
Ebner E, Mason TL, Mennucchi L, Schatz G (1973) J Biol Chem 248:5360–5378
Tzagoloff A, Akai A, Needleman RB (1975) J Biol Chem 250:8228–8235
Schweizer E, Demmer W, Holzner U, Tahedl H (1977) In: Bandlow W, Schweyen RJ, Wolf K, Kaudewitz F (eds) Mitochondria 1977: Genetics and biogenesis of mitochondria. Walter de Gruyter, Berlin New York, p 91
Sherman F, Stewart JW (1966) Proc Natl Acad Sci USA 55:1498–1504
Schweyen RJ, Steyrer U, Kaudewitz F, Dujon B, Slonimski PP (1976) Mol Gen Genet 146:117–132
Wolf K, Dujon B, Slonimski PP (1973) Mol Gen Genet 125:53–90
Boeker-Schmitt E (1980) Dissertation, Genetisches Institut München
Sipiczky M, Ferenczy L (1978) Mutat Res 50:163–173
Bachofen V, Schweyen RJ, Wolf K, Kaudewitz F (1972) Z Naturforsch 27b:252–256
Ogur M, Jahn RS, Nagai S (1975) Science 169:339–344
Lang B (in preparation)
Kitamura, Kaneko, Yamamoto (1974) Lysis of viable yeast cells by enzymes of Arthrobacter luteus. J Gen Appl Microbiol 20:71–85
Lang B (in preparation)
Lang B, Burger G, Bandlow W (1974) Biochem Biophys Acta 368:71–85
Beggs JD (1978) Nature 275:104–109
Chevallier MR, Bloch JC, Lacroute F (1980) Gene 11:11–19
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Lang, B.F., Kaudewitz, F. Cytochrome c 1-deficient mutants in Saccharomyces cerevisiae . Curr Genet 6, 229–235 (1982). https://doi.org/10.1007/BF00390343
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00390343