Summary
Three allelic mutations of a new yeast gene, which we have named REV7, have been isolated by testing 313 methyl methane sulfonate sensitive mutants for UV-induced reversion of a lys2 allele. Rev7 mutants are markedly deficient with respect to UV-induced reversion of lys2, are slightly sensitive to UV and appear to be in the RAD6 epistasis group for UV survival. Rev7-1, which is probably an amber mutation, does not appear to affect sporulation in homozygous diploids. The REV7 gene is located about 12 cM distal to HIS5 on chromosome IX.
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Communicated by C. Auerbach
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Lawrence, C.W., Das, G. & Christensen, R.B. REV7, a new gene concerned with UV mutagenesis in yeast. Molec. Gen. Genet. 200, 80–85 (1985). https://doi.org/10.1007/BF00383316
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DOI: https://doi.org/10.1007/BF00383316