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X-Ray sensitivity of Escherichia coli lysogenic for bacteriophage P2

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Summary

Strains of Escherichia coli C or K lysogenic for the non-inducible phage P2 show a lower survival following X-ray irradiation as compared to nonlysogenic strains. This difference in X-ray sensitivity is not accompanied by a significant difference in X-ray induced mutability. The capacity of X-irradiated P2 lysogens to multiply any of a number of unirradiated infecting phages is severely impaired. These effects of X-ray treatment can be most simply explained as a consequence of the fact that protein and RNA syntheses are strongly inhibited in P2 lysogens after X-irradiation. All the above events specifically occurring in X-rayed P2 lysogens are dependent on the P2 gene old.

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Authors and Affiliations

  1. Instituto di Genetica, Università di Milano, Via Celoria 10, I-20133, Milano, Italy

    Daniela Ghisotti, Sandro Zangrossi & Gianpiero Sironi

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  1. Daniela Ghisotti
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  2. Sandro Zangrossi
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  3. Gianpiero Sironi
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Communicated by A.J. Clark

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Ghisotti, D., Zangrossi, S. & Sironi, G. X-Ray sensitivity of Escherichia coli lysogenic for bacteriophage P2. Molec. Gen. Genet. 169, 229–235 (1979). https://doi.org/10.1007/BF00382268

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  • DOI: https://doi.org/10.1007/BF00382268

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