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Correspondence of the monocyte antigen HMA-1 to the non-HLA antigen 9a

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Abstract

Monocyte-specific antibodies are detrimental to bone marrow and renal transplantation. By using human antimonocyte sera we were able to identify two monocyte-specific antigens, human monocyte antigen 1 and 2 (HMA-1 and HMA-2). The presence of HMA-1 and HMA-2 was compared with the presence of several non-HLA antigens. In panel and inhibition studies, HMA-1 corresponded to the previously described non-HLA granulocyte antigen 9a. Absorption studies showed that HMA-1 and 9a were both present on granulocytes and monocytes. The clinical relevance of these antigens is discussed.

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Jager, M.J., Claas, F.H.J., Witvliet, M. et al. Correspondence of the monocyte antigen HMA-1 to the non-HLA antigen 9a. Immunogenetics 23, 71–77 (1986). https://doi.org/10.1007/BF00377964

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  • DOI: https://doi.org/10.1007/BF00377964

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