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Stability analysis of a binary culture chemostat experiencing biofilm formation

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Abstract

Time-dependent biofilm formation effects on continuous fermenter operation are modelled here for a binary culture of microorganisms growing on a single substrate. Dynamic computer solutions are detailed for a mixed culture of one microbe a having a higher growth rate than a second microbe b for two hypothetical scenarios of microbe b having different magnitudes of cellular deposition rate. A stability analysis of the resultant steady-states is also provided. Biofilm effects on the estimation of kinetic and stoichiometric parameters in a chemostat plus the impact of biofilms on mixed culture dynamics are discussed.

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  1. Center of Biochemical Engineering School of Engineering, Duke University, 27706, Durham, North Carolina, USA

    J. D. Bryers

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Bryers, J.D. Stability analysis of a binary culture chemostat experiencing biofilm formation. Bioprocess Eng. 1, 3–11 (1986). https://doi.org/10.1007/BF00369459

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  • DOI: https://doi.org/10.1007/BF00369459

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