Abstract
An attempt was made to quantify the postsynaptic current based on the experimental data of the voltage clamp method. The conductance change in postsynaptic membrane was derived from the postsynaptic conductance of voltage clamped postsynaptic membrane, then it's temporal characteristics and dependence on the clamped voltage have been quantified. The temporal characteristics was found to be explained by the introduction of two schematic operators, active and inactive. This idea was applied to a simple electrical circuit model of the postsynaptic cells. Besides the change in postsynaptic potentials of normal synapse in excitable state was culculated as its application.
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Yagi, H., Hashimoto, T. & Sugimoto, K. Quantitative description of end plate current and its reconstruction. Biol. Cybernetics 26, 125–129 (1977). https://doi.org/10.1007/BF00365223
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DOI: https://doi.org/10.1007/BF00365223