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99mTc-DTPA and 99mTc-DMSA renal gamma imaging in the surveillance of patients with conduit urinary diversion

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Abstract

We studied renal anatomy and function using 99mTc-2-3 dimercaptosuccinic acid (DMSA) and 99mTc-diethylenetriaminepentaacetic acid (DTPA) in 27 patients with conduit urinary diversion. In this condition, free ureteral reflux is often associated with bacteriuria, and these factors are thought to precipitate progressive renal deterioration. Gamma-camera images provided valuable information concerning the structure of the renal parenchyma, the function of individual kidneys and possible ureteral obstruction, thus helping us to decide whether or not to instigate further treatment. The information gained using renal gamma imaging with 99mTc-DTPA and 99mTc-DMSA was complementary and partly overlapping. We preferred the use of 99mTc-DTPA because of its ability to visualise the ureters and the region of ureteroconduit anastomosis. Using diuretic medication, we were able to differentiate true ureteral obstruction from atony in 9 patients using 99mTc-DTPA.

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References

  • Belis JA, Belis TE, Lai JCW, Goodwin CA, Gabriele OF (1982) Radionuclide determination of individual kidney function in the treatment of chronic renal obstruction. J Urol 127:636–641

    Google Scholar 

  • Bergman B, Kaijser B, Nilson AE (1979) Conduit urinary diversion and urinary tract infection. Scand J Urol Nephrol 13:71–77

    Google Scholar 

  • Bratt CG, Larsson J, White T (1981) Scintillation camera renography with 99mTc-DTPA and 131I-Hippuran. Scand J Clin Lab Invest 41:189–197

    Google Scholar 

  • Bricker EM (1950) Bladder substitution after pelvic evisceration. Surg Clin North Am 30:1511–1521

    Google Scholar 

  • Bricker EM (1980) Current status of urinary diversion. Cancer 45:2986–2991

    Google Scholar 

  • Bricker EM, Butcher H, McAfee CA (1954) Late results of bladder substitution with isolated ileal segments. Surg Gynecol Obstet 99:469–482

    Google Scholar 

  • Bröchner-Mortensen J, Rödbro P (1976) Comparison between total and renal plasma clearance of 51Cr-EDTA. Scand J Clin Lab Invest 36:247–249

    Google Scholar 

  • Bröchner-Mortensen J, Jensen S, Rödbro P (1977a) Delimitation of plasma creatinine concentration values for assessment of relative renal function. Scand J Urol Nephrol 11:257–262

    Google Scholar 

  • Bröchner-Mortensen J, Jensen S, Rödbro P (1977b) Assessment of renal function from plasma creatinine in adult patients. Scand J Urol Nephrol 11:263–270

    Google Scholar 

  • Buck AC, MacLeod MA, Blacklock NJ (1980) The advantages of 99mTc-DTPA (Sn) in dynamic renal scintigraphy and measurement of renal function. Br J Urol 52:174–186

    Google Scholar 

  • Campbell JE, Oliver JA, McKay DE (1965) Dynamics of ileal conduits. Radiology 85:338–342

    Google Scholar 

  • Daly MJ, Henry RE (1981) Defining renal anatomy and function with 99mTc-dimercaptosuccinic acid: Clinical and renographic correlation. J Urol 126:5–9

    Google Scholar 

  • Enlander D, Weber PM, dos Remedios LV (1974) Renal cortical imaging in 35 patients: Superior quality with 99mTc-DMSA. J Nucl Med 15:743–749

    Google Scholar 

  • Gates GF (1982) Glomerular filtration rate: Estimation from fractional renal accumulation of 99mTc-DTPA (stannous). AJR 138:565–570

    Google Scholar 

  • Guinan PD, Moore RH, Neter E, Murphy GD (1972) The bacteriology of ileal conduit urine in man. Surg Gynecol Obstet 134:78–82

    Google Scholar 

  • Holten J, Storm HH (1979) Kidney scintigraphy with 99mTc-DMSA and 131I-hippurate. Scand J Urol Nephrol 13:275–281

    Google Scholar 

  • Johansson RS, Falch DK (1978) 113mIn-DTPA, a useful compound for the determination of glomerular filtration rate (GFR). Eur J Nucl Med 3:179–181

    Google Scholar 

  • Kirchner PT, James AE Jr, Reba RC, Wagner HN Jr (1975) Patterns of excretion of radioactive chelates in obstructive uropathy. Radiology 114:655–661

    Google Scholar 

  • Lin TH, Khentigan A, Winchell HS (1974) A 99mTc-chelate substitute for organoradiomercurial renal agents. J Nucl Med 15:34–35

    Google Scholar 

  • Månsson W, Colleen S, Forsberg L, Larsson I, Sundin T, White T (1984) Renal function after urinary diversion. Scand J Urol Nephrol 18:307–315

    Google Scholar 

  • Meldolesi U, Roncari G, Conte L, Mobelli L (1975) Renal plasma flow and glomerular filtration rate as estimated through double radiocompound renography. Nucl Med 13:279–287

    Google Scholar 

  • Middleton AW Jr, Hendren WH (1976) Ileal conduits in children at the Massachusetts General Hospital from 1955 to 1970. J Urol 115:591–595

    Google Scholar 

  • Piepsz A, Denis R, Ham HR, Dobbeleir A, Schulman C, Erbsmann F (1978) A simple method for measuring separate glomerular filtration rate using a single injection of 99mTc-DTPA and the scintillation camera. J Pediatr 93:769–774

    Google Scholar 

  • Pieretti R, Gilday D, Jeffs R (1974) Differential kidney scan in pediatric urology. Urology 4:665–668

    Google Scholar 

  • Richie JP, Skinner DG, Waisman J (1974) The effect of reflux on the development of pyelonephritis in urinary diversion: An experimental study. J Surg Res 16:256–261

    Google Scholar 

  • Rickwood AMK (1982) Urinary diversion in children. In: Ashken MH (ed) Urinary diversion. Springer, Berlin Heidelberg New York, p 41

    Google Scholar 

  • Sample FW (1980) Renal, adrenal, retroperitoneal and scrotal ultrasonography. In: Sarti DA, Sample FW (eds) Diagnostic ultrasound. Text and cases. G.K. Hall, Boston, pp 268–411

    Google Scholar 

  • Scharf SC, Blaufox MD (1982) Radionuclides in the evaluation of urinary obstruction. Semin Nucl Med 12:254–264

    Google Scholar 

  • Schmidt JD, Hawtrey CE, Flocks RH, Culp DA (1973) Complications, results and problems of ileal conduit diversions. J Urol 109:210–216

    Google Scholar 

  • Tamminen TE, Riihimäki EJ, Tähti EE (1978) A gamma camera method of quantitation of split renal function in children followed for vesicoureteric reflux. Pediatr Radiol 7:78–84

    Google Scholar 

  • Taylor A Jr. (1982) Quantitation of renal function with static imaging agents. Semin Nucl Med 12:330–344

    Google Scholar 

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Lindell, O., Kivisaari, A. & Lehtonen, T. 99mTc-DTPA and 99mTc-DMSA renal gamma imaging in the surveillance of patients with conduit urinary diversion. Eur J Nucl Med 12, 80–85 (1986). https://doi.org/10.1007/BF00364734

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  • DOI: https://doi.org/10.1007/BF00364734

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