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Klinische Erfahrung mit Benzolsulfonsäurechlorid

Clinical experience with benzene sulfonyl chloride

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Abstract

The clinical development of a percutaneous benzene sulfonyl chloride absorption, which can also occur on the mucous membrane, has a biological effect on the skin and results in reversible toxic damage to the liver; three such cases are described.

Two patients experienced Very severe shock which was brought under control after 1 to 1.5 hrs.

A possible allergic genesis reaction of an immediate type is discussed.

Zusammenfassung

An drei Fällen schildert der Autor den klinischen Verlauf einer perkutanen und über die Schleimhaut erfolgten Aufnahme Von Benzolsulfonsäurechlorid, die zu biologischer Einwirkung auf die Haut und toxischer reversibler Leberschädigung führte.

In zwei Fällen entwickelte sich ein schwerster Schock, der nach 1 bis 1,5 Std beherrscht wurde.

Es wird eine mögliche allergische Genese des Geschehens von Soforttyp diskutiert.

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Literatur

  • Arbesman, C.E., Koji, Ito, Wypych, J. I., Wicher, K.: Measurement of serum IgE by a one-step single radial radiodiffusion method. J. Allergy 49, 72–80 (1972)

    Google Scholar 

  • Centifanto, Y. M., Kaufman, H. E.: A simplified method for measuring human IgE. J. Immunol. 107, 608–609 (1971)

    Google Scholar 

  • Crabtree, H. G.: Retardation of the rate of tumor induction by hydroglyzing chlor-compounds. Cancer Res. 1, 39–43 (1941)

    Google Scholar 

  • Gray, C. H.: Laboratory handbook of toxic agents. London: The Royal Institute of Chemistry 1966

    Google Scholar 

  • Hirade, J., Ninomiya, A.: Studies on the mechanism of the toxic action of organic halogen compounds. J. Biochem. 37, 19–33 (1950)

    Google Scholar 

  • Hodge, H. C., Sterner, J. H.: American Industrial Hygiene Association. Quarterly 10, 93 (1943)

    Google Scholar 

  • Jacobs, D., Houri, M., Landon, J., Merret, T. G.: Circulating levels of immunoglobulin E in patients with cancer. Lancet 1972, 1059–1061

  • Ślusarczyk-Źałlobna, A., Szendzikowski, S., Zwierzchowski, Z., Kuczma, I.: Beurteilung der akuten toxischen Einwirkung von Benzolsulfochlorid (polnisch). Med. Pracy 20, 513–518 (1969)

    Google Scholar 

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Stasik, M.J. Klinische Erfahrung mit Benzolsulfonsäurechlorid. Arch. Toxicol. 33, 123–127 (1975). https://doi.org/10.1007/BF00353237

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  • DOI: https://doi.org/10.1007/BF00353237

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