Skip to main content
Log in

Absence of mutagenic activity and a short-term toxicity study of beet pigments as food colorants

  • Short Communications
  • Published:
Archives of Toxicology Aims and scope Submit manuscript

Abstract

Beet colorant was tested for mutagenic activity in five S. typhimurium strains. The absence of mutagenic activity was found with or without S-9 rat liver fractions.

Groups of six rats were fed red beet colorant preparations containing 2,000 ppm betalains in the diet for 7 days. No significant differences were noted in body weight gains, feed consumption, or gross pathological alterations compared to the controls.

These preliminary toxicological results indicate the potential usage of betalain pigments as a food colorant, but further long term investigations are warranted.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Adams JP, von Elbe JH, Amundson CH (1976) Production of a betacyanine concentrate by fermentation of red beet juice with Candida utilis. J Food Sci 41:78–81

    Google Scholar 

  • Ames BN, McCann J, Yamasaki E (1975) Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. Mutat Res 31:347–364

    Google Scholar 

  • Anonymous (1978) Red 40 safety in doubt at NCI. Fd Eng 50:35

    Google Scholar 

  • de Serres FJ, Shelby MD (1979) Recommendations on data production and analysis using the Salmonella/microsome mutagenicity assay. Mutat Res 64:159–165

    Google Scholar 

  • Forrai G, Vagujfalvi D, Bolcskey P (1968) Betaninuria in childhood. Acta Paediatr Acad Sci Hung 9:43–51

    Google Scholar 

  • Krantz C, Monier M, Wahlstrom B (1980) Absorption, excretion, metabolism and cardiovascular effects of beetroot extract in the rat. Fd Cosmet Toxicol 18:363–366

    Google Scholar 

  • Vergeront TA, von Elbe JH, Amundson CH (1980) Large-scale isolation of betalaines by gel filtration. Process Biochem 15:2–6

    Google Scholar 

  • von Elbe JH (1977) The betalaines. In: Furia T (ed) Current aspects of food colorants. CRC Press Inc., Cleveland, OH, pp 29–39

    Google Scholar 

  • Watson WC (1964) The metabolism of betanin. Biochem J 90:3

    Google Scholar 

  • Watson WC, Luke RG, Inall JA (1963) Beeturia: Its incidence and a clue to its mechanism. Br Med J 2:971–973

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

von Elbe, J.H., Schwartz, S.J. Absence of mutagenic activity and a short-term toxicity study of beet pigments as food colorants. Arch Toxicol 49, 93–98 (1981). https://doi.org/10.1007/BF00352077

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00352077

Key words

Navigation