Abstract
Beet colorant was tested for mutagenic activity in five S. typhimurium strains. The absence of mutagenic activity was found with or without S-9 rat liver fractions.
Groups of six rats were fed red beet colorant preparations containing 2,000 ppm betalains in the diet for 7 days. No significant differences were noted in body weight gains, feed consumption, or gross pathological alterations compared to the controls.
These preliminary toxicological results indicate the potential usage of betalain pigments as a food colorant, but further long term investigations are warranted.
References
Adams JP, von Elbe JH, Amundson CH (1976) Production of a betacyanine concentrate by fermentation of red beet juice with Candida utilis. J Food Sci 41:78–81
Ames BN, McCann J, Yamasaki E (1975) Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. Mutat Res 31:347–364
Anonymous (1978) Red 40 safety in doubt at NCI. Fd Eng 50:35
de Serres FJ, Shelby MD (1979) Recommendations on data production and analysis using the Salmonella/microsome mutagenicity assay. Mutat Res 64:159–165
Forrai G, Vagujfalvi D, Bolcskey P (1968) Betaninuria in childhood. Acta Paediatr Acad Sci Hung 9:43–51
Krantz C, Monier M, Wahlstrom B (1980) Absorption, excretion, metabolism and cardiovascular effects of beetroot extract in the rat. Fd Cosmet Toxicol 18:363–366
Vergeront TA, von Elbe JH, Amundson CH (1980) Large-scale isolation of betalaines by gel filtration. Process Biochem 15:2–6
von Elbe JH (1977) The betalaines. In: Furia T (ed) Current aspects of food colorants. CRC Press Inc., Cleveland, OH, pp 29–39
Watson WC (1964) The metabolism of betanin. Biochem J 90:3
Watson WC, Luke RG, Inall JA (1963) Beeturia: Its incidence and a clue to its mechanism. Br Med J 2:971–973
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
von Elbe, J.H., Schwartz, S.J. Absence of mutagenic activity and a short-term toxicity study of beet pigments as food colorants. Arch Toxicol 49, 93–98 (1981). https://doi.org/10.1007/BF00352077
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00352077