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Smooth muscle cells in aortic cultures of untreated and cholesterol-fed rabbits

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Summary

Smooth muscle cells were identified in aortic cultures from which the explants had not been removed. They appeared in cultures from intact aorta within 10 days and in cultures from aorta with plaques in 15 days. Myometrial smooth muscle cells grew within 2–4 days.

Differences in growth rate of smooth muscle cells from various sources were explained as were differences in growth of aortic and subcutaneous fibroblasts. Morphologic characteristics of smooth muscle cells and fibroblasts were described in details. Peculiarities of migration of smooth muscle cells in vitro were discussed.

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References

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Authors and Affiliations

  1. Dover Medical Research Center, Inc., Dover, Del., USA

    Tatsuo Kasai & O. J. Pollak

Authors
  1. Tatsuo Kasai
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  2. O. J. Pollak
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Additional information

This study was supported by grant HE-02534 from the National Heart Institute.

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Kasai, T., Pollak, O.J. Smooth muscle cells in aortic cultures of untreated and cholesterol-fed rabbits. Zeitschrift für Zellforschung 62, 743–752 (1964). https://doi.org/10.1007/BF00342181

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  • DOI: https://doi.org/10.1007/BF00342181

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