Abstract
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1.
The circadian patterns of clinically relevant parameters were studied in 109 young, healthy soldiers.
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2.
Erythrocytes, hematocrit, creatinine and cortisol exhibited very stable rhythmic patterns which were found by continuous examinations of the same persons as well as in examinations of different persons at different times.
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3.
The rhythmic patterns of leukocytes, blood glucose and body temperature were strongly influenced by stress caused by the first confrontation with an unknown hospital-like situation or by pain caused by blood sampling.
Zusammenfassung
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1.
Das zirkadiane Muster klinisch wichtiger Parameter wurde bei 109 jungen, gesunden Soldaten untersucht.
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2.
Erythrozyten, Hämatokrit, Kreatinin und Cortisol zeigten ein sehr stabiles Rhythmusmuster, das sowohl durch kontinuierliche Untersuchung der gleichen Person als auch durch die Untersuchung verschiedener Probanden zu aufeinanderfolgenden Zeiten gefunden werden konnte.
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3.
Das tagesrhythmische Verhalten von Leukozyten, Blutzucker und Körpertemperatur wurden durch den Streß der ersten Konfrontation mit einer ungewohnten Krankenhaussituation oder einer schmerzhaften Blutabnahme stark beeinflußt.
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Read at the Symposium “Relevance of Chronobiology for Toxicology and Pharmacology” held at the 16th Spring Meeting of the Deutsche Pharmakologische Gesellschaft, Section: Toxicology, March 6, 1975, Mainz
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Steinbach, G., Hilfenhaus, M., Mayersbach, H.v. et al. Circadian influences on clinical values in man. Arch. Toxicol. 36, 317–325 (1976). https://doi.org/10.1007/BF00340537
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DOI: https://doi.org/10.1007/BF00340537
Key words
- Circadian rhythm
- Influence of blood sampling
- Hematologic and clinically chemical parameters
- Body temperature