Summary
We have isolated a number of heat sensitive mutants of the yeast, Saccharomyces cervisiae. These mutants are sensitive to heat inactivation at 52°C and 37°C. They are also sensitive to the monofunctional alkylating agent EMS and are sensitive to gamma rays at low doses. The results suggest a common step in the repair of some of the damage induced by heat, alkylating agents and ionizing radiation.
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Communicated by F. Kaudewitz
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Evans, W.E., Parry, J.M. Isolation, genetics and survival characteristics of thermo-sensitive mutants of yeast. Molec. gen. Genet. 134, 333–344 (1974). https://doi.org/10.1007/BF00337468
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DOI: https://doi.org/10.1007/BF00337468