Summary
The duration of the cell cycle, macronuclear DNA synthetic period, presynthetic and postsynthetic period was determined in Tetrahymena at different temperatures in a medium containing 0.4% protein. The relative length of all these phases remains constant over the range from 19°C to 27°C. The implication of these findings with the control of the cell cycle and its parts is discussed.
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Cameron, I. L., and D. S. Nachtwey: DNA synthesis in relation to cell division in Tetrahymena pyriformis. U.S. Naval Radiological Defense Laboratory, San Francisco: T R 1084, p. 1–22 (1966).
Cerroni, R. E., and E. Zeuthen: Inhibition of makromolecular synthesis and of cell division in synchronized Tetrahymena. Exp. Cell Res. 26, 604–605 (1962).
Cleffmann, G.: Die Schwelle der Hemmung der Nucleinsäuresynthese und der Teilung durch Actinomycin bei Tetrahymena pyriformis. Z. Zellforschung. 67, 343–350 (1965).
—: Bildung zusätzlicher DNS nach Blockierung der Zellteilung von Tetrahymena durch Actinomycin. Z. Zellforsch. 70, 290–297 (1966).
Howard, A., and S. R. Pelc: Synthesis of deoxyribonucleic acid in normal and irradiated cells and its relation to chromosome breakage. Heredity, Suppl. 6, 261–273 (1953).
Lazarus, L. H., M. R. Levy, and O. H. Scherbaum: Inhibition of synchronized cell division in Tetrahymena by actinomycin D. Exp. Cell Res. 36, 672–676 (1964).
Nygaard, O. F., and S. Güttes: Effects of ionizing radiations on a slime mould with synchronous mitosis. Int. J. Radiat. Biol. 5, 33–44 (1962).
Prescott, D. M.: Relation between multiplication rate and temperature in Tetrahymena pyriformis, strains HS and GL. J. Protozool. 4, 252–257 (1957).
Sachsenmeier, W., and H. P. Rusch: The effect of 5-Fluoro-2′-deoxyuridine on synchronous mitosis in Physarum polycephalum. Exp. Cell Res. 36, 124–133 (1964).
Scherbaum, O. H.: The content and composition of nucleic acids in normal and synchronously dividing cultures of Tetrahymena pyriformis. Exp. Cell Res. 13, 24–30 (1957).
Stone, G. E., and I. L. Cameron: Methods for using Tetrahymena in studies of the normal cell cycle. In: D. M. Prescott, Methods in cell physiology, vol. 1, p. 127–140. New York: Acad. Press 1964.
—, O. L. Miller, and D. M. Prescott: H3-Thymidine derivative pools in relation to macronuclear DNA-synthesis in Tetrahymena pyriformis. J. Cell Biol. 25, 171–177 (1965).
Watanabe, Y., and M. Ikeda: Isolation and characterisation of the division protein in Tetrahymena pyriformis. Exp. Cell Res. 39, 443–452 (1962).
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Mit dankenswerter Unterstützung durch die Deutsche Forschungsgemeinschaft.
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Cleffmann, G. Temperaturabhängigkeit der Phasen des Teilungszyklus von Tetrahymena pyriformis HSM. Zeitschrift für Zellforschung 79, 599–602 (1967). https://doi.org/10.1007/BF00336316
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DOI: https://doi.org/10.1007/BF00336316