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Über die Kerngebiete des menschlichen Hirnstammes

I. Oliva inferior, Nucleus conterminalis und Nucleus vermiformis corporis restiformis

On the nuclei of the human brain stem

I. Oliva inferior, nucleus conterminalis and nucleus vermiformis corporis restiformis

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Summary

The three dimensional shape of the oliva inferior, nucleus conterminalis, and a hitherto unknown nucleus in the corpus restiforme is described. The author applied a new method allowing to stain selectively nuclei of the human brain in thick slices (1000 μ). The sections are studied with the binoculars at low magnifications and can substitute time consuming reconstructions. Besides the distribution of lipofuscin as element of the chemoarchitecture of the brain stem is investigated.

The nucleus principalis is divided into 2, the dorsal accessory oliva into 4, and the medial accessory oliva into 14 areas. The rather complicated shape of the nuclei is interpreted as an expression of functional differences of the various areas. The distributional patterns of different afferent and efferent fibers in the oliva inferior of the cat, as shown by Brodai and his collaborators is hypothetically transferred to a scheme of the subdivisions of the human oliva.

Zusammenfassung

Die räumliche Gestalt der unteren Olive, des Nucleus conterminalis und eines bisher unbekannten Kerngebietes im Corpus restiforme wird beschrieben. Dabei wird eine neue Methode angewendet, die es gestattet, Kerngebiete des menschlichen Gehirnes in sehr dicken Schnitten (1000 μ) elektiv anzufärben. Die aufgehellten Präparate werden mit der Stereolupe betrachtet und können zeitraubende plastische Rekonstruktionen ersetzen. Zugleich wird das Pigmentbild der Kerngebiete, als Teil der Chemoarchitektonik, studiert.

Die Hauptolive wird in 2, die dorsale Nebenolive in 4 und die mediale Nebenolive in 14 Areale unterteilt. Die komplizierte Kerngestalt wird als Ausdruck funktioneller Unterschiede der einzelnen Areale verstanden. Die von Brodal u. Mitarb. im Tierversuch ermittelten Verteilungsmuster der Afferenzen und Efferenzen innerhalb der unteren Olive werden in einem hypothetischen Schema auf die Untergliederungen der menschlichen Olive übertragen.

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Literatur

  • Berman, A. L.: The brain stem of the cat. Madison-Milwaukee-London: The University of Wisconsin Press 1968.

    Google Scholar 

  • Braak, H.: Über die Gestalt des neurosekretorischen Zwischenhirn-Hypophysen-Systems von Spinax niger. Z. Zellforsch. 58, 265–276 (1962).

    Google Scholar 

  • Brodal, A.: Experimentelle Untersuchungen über die olivo-cerebellare Lokalisation. Z. ges. Neurol. Psychiat. 169, 1–153 (1940).

    Google Scholar 

  • —, Walberg, F., Blackstad, T. H.: Termination of spinal afferents to inferior olive in cat. J. Neurophysiol. 13, 431–454 (1950).

    Google Scholar 

  • Ebbesson, S. O. E.: A connection between the dorsal column nuclei and the dorsal accessory olive. Brain Res. 8, 393–397 (1968).

    Google Scholar 

  • Elftman, H.: Aldehydfuchsin for pituitary cytochemistry. J. Histochem. Cytochem. 7, 98–100 (1959).

    Google Scholar 

  • Hand, P., Liu, C. N.: Efferent projections of the nucleus gracilis. Anat. Rec. 154, 353–354 (1966).

    Google Scholar 

  • Harkmark, W.: Cell migrations from the rhombic lip to the inferior olive, the nucleus raphe and the pons. A morphological and experimental investigation on chick embryos. J. comp. Neurol. 100, 115–209 (1954).

    Google Scholar 

  • Harkmark, W.: The influence of the cerebellum on development and maintenance of the inferior olive and the pons. J. exp. Zool. 131, 333–371 (1956).

    Google Scholar 

  • Jacobsohn, L.: Über die Kerne des menschlichen Hirnstammes (der Medulla oblongata, des Pons und des Pedunculus). Zbl. ges. Neurol. Psychiat. 28, 674–679 (1909).

    Google Scholar 

  • Jansen, J., Brodal, A.: Das Kleinhirn. In: Handbuch der mikroskopischen Anatomie des Menschen (Ed.: W. Bargmann) IV/8. Berlin-Göttingen-Heidelberg: Springer 1958.

    Google Scholar 

  • Kankeleit, O.: Zur vergleichenden Morphologie der unteren Säugerolive mit Bemerkungen über Kerne in der Oliven-Peripherie. Inaug. Diss. Berlin 1913. Arch. Anat. Physiol. (Anat. Abt.) (1913).

  • Kooy, F. H.: The inferior olive in vertebrates. Thesis Haarlem: De Erven F. Bohn 1916.

    Google Scholar 

  • —: The inferior olive in vertebrates. Folia neuro-biol. (Lpz.) 10, 205–369 (1917).

    Google Scholar 

  • —: The inferior olive in Cetacea. Folia neurobiol. (Lpz.) 11, 647–664 (1920).

    Google Scholar 

  • Korneliussen, H. K., Jansen, J.: The morphogenesis and structure of the inferior olive of Cetacea. J. Hirnforsch. 7, 301–314 (1964).

    Google Scholar 

  • Mareschal, P.: L'olive bulbaire: Anatomie, ontogénèse, phylogénèse, physiologie et physiopathologie. Paris: G. Doin 1934.

    Google Scholar 

  • Marsden, C. D., Rowland, R.: The mammalian pons, olive and pyramid. J. comp. Neurol. 124, 175–187 (1965).

    Google Scholar 

  • Meessen, H., Olszewski, J.: A cytoarchitectonic atlas of the rhombencephalon of the rabbit. Basel-New York: S. Karger 1949.

    Google Scholar 

  • Mizuno, N.: An experimental study of the spino-olivary fibers in the rabbit and the cat. J. comp. Neurol. 127, 267–292 (1966).

    Google Scholar 

  • Noback, C. R.: Brain of a gorilla. II. Brain stem nuclei. J. comp. Neurol. 111, 345–386 (1959).

    Google Scholar 

  • Ogawa, T.: The tractus tegmenti medialis and its connections with the inferior olive in the cat. J. comp. Neurol. 70, 181–190 (1939).

    Google Scholar 

  • Olszewski, J., Baxter, D.: Cytoarchitecture of the human brain stem. New York-Basel: S. Karger 1954.

    Google Scholar 

  • Oscarsson, O.: Termination and functional organization of a dorsal spino-olivo cerebellar path. Brain Res. 5, 531–534 (1967).

    Google Scholar 

  • —, Uddenberg, N.: Somatotopic termination of spino-olivo cerebellar path. Brain Res. 3, 204–207 (1966).

    Google Scholar 

  • Pearse, A. G. E.: Histochemistry. London: J. and A. Churchill 1960.

    Google Scholar 

  • Riley, H. A.: An atlas of the basal ganglia, brain stem and spinal cord. Baltimore: Williams & Wilkins Co 1943.

    Google Scholar 

  • Rossbach, R.: Das neurosekretorische Zwischenhirnsystem der Amsel (Turdus merula L.) im Jahresablauf und nach Wasserentzug. Z. Zellforsch. 71, 118–145 (1966).

    Google Scholar 

  • Scheibel, M. E., Scheibel, A. B.: The inferior olive. A Golgi study. J. comp. Neural. 102, 77–131 (1955).

    Google Scholar 

  • —, Walberg, F., Brodal, A.: Areal distribution of axonal and dendritic patterns in inferior olive. J. comp. Neurol. 106, 21–49 (1956).

    Google Scholar 

  • Taber, E.: The Cytoarchitecture of the brain stem of the cat. J. comp. Neurol. 116, 27–69 (1961).

    Google Scholar 

  • Taber Pierce, E.: Histogenesis of the nuclei griseum pontis, corporis ponto-bulbaris and reticularis tegmenti pontis (Bechterew) in the mouse. An autoradiographic study. J. comp. Neurol. 126, 219–240 (1966).

    Google Scholar 

  • Tcheng, K. T.: Some observations on the lipofuscin pigments in the pyramidal and Purkinje cells of the monkey. J. Hirnforsch. 6, 321–326 (1964).

    Google Scholar 

  • Verhaart, W. J. C.: Anatomy of the brain stem of the elephant. J. Hirnforsch. 5, 455–524 (1962).

    Google Scholar 

  • —: The central tegmental tract. J. comp. Neurol. 90, 173–192 (1949).

    Google Scholar 

  • Vogt-Nilsen, L.: The inferior olive in birds. A comparative morphological study. J. comp. Neurol. 101, 447–481 (1954).

    Google Scholar 

  • Walberg, F.: Descending connections to the inferior olive. In: Aspects of cerebellar anatomy (eds.: J. Jansen, and A. Brodal). Oslo: Johan Grundt Tanum Forlag 1954.

    Google Scholar 

  • —: Descending connections to the inferior olive. An experimental study in the cat. J. comp. Neurol. 104, 77–173 (1956).

    Google Scholar 

  • Walberg F.: Further studies on the descending connections to the inferior olive. Reticuloolivary fibers. An experimental study in the cat. J. comp. Neurol. 114, 79–87 (1960).

    Google Scholar 

  • Weed, A.: A reconstruction of the nuclear masses in the lower position of the human brain stem. Publ. No 191 of the Carnegie Inst. Wash. (1914).

  • Wolf, A., Pappenheimer, A. M.: Occurence and distribution of acid fast pigment in the central nervous system. J. Neuropath exp. Neurol. 4, 402–406 (1946).

    Google Scholar 

  • Yoda, S.: Über die Kerne der Medulla oblongata der Katze. Z. mikr.-anat. Forsch. 48, 529–582 (1940).

    Google Scholar 

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  1. Anatomisches Institut der Universität Kiel, Deutschland

    H. Braak

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  1. H. Braak
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Mit dankenswerter Unterstützung durch die Deutsche Forschungsgemeinschaft.

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Braak, H. Über die Kerngebiete des menschlichen Hirnstammes. Z. Zellforsch. 105, 442–456 (1970). https://doi.org/10.1007/BF00335466

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  • DOI: https://doi.org/10.1007/BF00335466

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