Abstract
Heterozygotes for the dominant temperature sensitive mutant DTS-3 of Drosophila melanogaster die as third instar larvae when grown at 29° C. These larvae have grossly hypertrophied ring glands due to the growth of the prothoracic gland cells. The nuclei of the prothoracic glands possess polytene chromosomes which are as large as those of salivary gland nuclei. The banding pattern of these chromosomes is similar, if not identical, to that of salivary gland polytene chromosomes but the puffing patterns are quite different. The salivary gland chromosomes of DTS-3/+ larvae also hypertrophy and lack the normal ecdysone induced puffs. Both the prothoracic gland and salivary gland chromosomes of these mutant larvae react to ecdysone in vitro by the induction of similar puffs.
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Holden, J.J., Ashburner, M. Patterns of puffing activity in the salivary gland chromosomes of Drosophila . Chromosoma 68, 205–227 (1978). https://doi.org/10.1007/BF00335417
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DOI: https://doi.org/10.1007/BF00335417