Summary
This study deals with the activity and distribution of the following tetrazolium (Nitro-BT) reductases in the hippocampal region of the rat: NADH-,NADPH-, α-glycerophosphate-, succinate-, the NAD+-linked lactate-, malate-, isocitrate-, glutamate-, β-HO-butyrate-, the NADP+-linked glucose-6-phosphate-, malate-, and isocitrate tetrazolium reductases. Several architectonic pictures of enzyme distribution were obtained, the number of which was further increased by adding to the incubation media phenazine methosulfate, which is supposed to function as an electron transport agent.
The laminar patterns of the various enzymes are described and commented on for each cortical area (p. 173). Then the patterns of parcellation resulting from the changes of laminar patterns are presented (p. 198). There is an excellent agreement between enzyme distribution and previously established architectural landmarks.
Finally some aspects of the observations are discussed and correlated to earlier enzyme histochemical and neurobiochemical studies.
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Supported by the Norwegian Research Council for Science and the Humanities and by The National Institute of Neurological Diseases and Blindness, U. S. Public Health Service, Grant NB 02215. This aid is gratefully acknowledged.
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Mellgren, S.I., Blackstad, T.W. Oxidative enzymes (tetrazolium reductases) in the hippocampal region of the rat. Z. Zellforsch. 78, 167–207 (1967). https://doi.org/10.1007/BF00334762
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DOI: https://doi.org/10.1007/BF00334762