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Four radiation sensitive mutants of Saccharomyces

Survival after UV- and X-ray-irradiation as well as UV-induced reversion rates from isoleucine-valine dependence to independence

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Summary

Three not closely linked genes (r s1 , r s2 and r s3 ), a mutation in each of which causes UV- and X-ray-sensitivity of the colony forming ability in haploid and homozygous diploid cells have been identified. In one gene, r s3 , two mutations have occurred independently. The effect of the mutated genes on long time repair processes as well as the effect on reversion rates from isoleucine-valine dependence to independence has been investigated. A model to explain the mechanisms changed by the mutated genes is discussed.

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Authors and Affiliations

  1. Institut für Biophysik der Freien Universität Berlin, Berlin, Germany

    D. Averbeck, W. Laskowski, F. Eckardt & E. Lehmann-Brauns

Authors
  1. D. Averbeck
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  2. W. Laskowski
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  3. F. Eckardt
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  4. E. Lehmann-Brauns
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Additional information

Communicated by F. Kaudewitz

Herrn Prof. Dr. Drs. h. c. Hans Nachtscheim zum 80. Geburtstag gewidmet.

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Averbeck, D., Laskowski, W., Eckardt, F. et al. Four radiation sensitive mutants of Saccharomyces . Molec. Gen. Genetics 107, 117–127 (1970). https://doi.org/10.1007/BF00333628

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  • DOI: https://doi.org/10.1007/BF00333628

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