Skip to main content
SpringerLink
Log in

Ultraviolet-induced mutation of bacteriophage λ

Induction by conjugation with ultraviolet irradiated donor cells

  • Published:
Molecular and General Genetics MGG Aims and scope Submit manuscript

Summary

Clear mutations of bacteriophage λ are increased within F- recipients in a cros s with ultraviolet (UV) irradiated F′ donors, without a direct UV irradiation of recipients. This mutagenesis occurs when phages are also irradiated with UV. The phenomenon is called an indirect UV induction of the mutation. The indirect UV induction of the mutation is also produced by a cross with UV irradiated Hfr male cells, and does not occur when the recipient is defective in recA gene.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Appleyard, R. J.: Segregation of lysogenicity during bacterial recombination in E. coli K12. Genetics 39, 429–439 (1954)

    Google Scholar 

  • Borek, E., Ryan, A.: The transfer of a biologically active irradiation product from cell to cell. Biochim. biophys. Acta (Amst.) 41, 67–73 (1960)

    Google Scholar 

  • Brooks, K., Clark, A. J.: Behaviour of bacteriophage in a recombination deficient strain of Escherichia coli. J. Virol. 1, 283–293 (1967)

    Google Scholar 

  • Clark, A. J., Margulies, A. D.: Isolation and characterization of recombination decifient mutants of Escherichia coli K12. Proc. nat. Acad. Sci. (Wash.) 53, 451–459 (1965)

    Google Scholar 

  • Defais, M., Fauquet, P., Radman, M., Errera, M.: Ultraviolet reactivation and ultraviolet mutagenesis of λ in deficient genetic systems. Virology 43, 495–503 (1971)

    Google Scholar 

  • Devoret, R., George, J.: Induction indirection indirecte du prophage λ par le rayonnement ultraviolet. Mutation Res. 4, 713–734 (1967)

    Google Scholar 

  • George, J.: Corrélation entra la disparition de l'induction indirecte du prophage λ et la restriction du DNA transmis à lá bactérie réceptrice inductible dans un croisement F+xF- hétérospécifique. C. R. Acad. Sci. (Paris) 262, 1805–1808 (1966)

    Google Scholar 

  • George, J., Devoret, R.: Conjugal transfer of UV-damaged F-prime sex factors and indirect induction of prophage λ. Molec. gen. Genet. 111, 103–119 (1971)

    Google Scholar 

  • George, J., Devoret, R., Radman M.: Indirect ultraviolet-Reactivation of phage λ. Proc. nat. Acad. Sci. (Wash.) 71 144–147 (1974)

    Google Scholar 

  • Miura, A., Tomizawa, J.: Studies on radiation-sensitive mutants of E. coli III. Participation of the rec system in induction of mutation by ultraviolet irradiation. Molec. gen. Genet. 103, 1–10 (1968)

    Google Scholar 

  • Miura, A., Tomizawa J.: Mutation and recombination of bacteriophage lambda: Effect of ultraviolet radiation. Proc. nat. Acad. Sci. (Wash.) 67 1722–1726 (1970)

    Google Scholar 

  • Monk, M., Devoret, R.: Induction ultraviolette par conjugaison du prophage par l'intermédaire du facteur colicinogène I. Ann. Inst. Pasteur 107, Suppl. No. 5, 163–173 (1964)

    Google Scholar 

  • Ogawa, H., Shimada, K., Tomizawa, J.: Studies on radiation-sensitive mutants of E. coli I. Mutants defective in the repair synthesis. Molec. gen. Genet. 101, 227–244 (1968)

    Google Scholar 

  • Ohki, M., Tomizawa, J.: Asymmetric transfer of DNA strands in bacterial conjugation. Cold Spr. Harb. Symp. quant. Biol. 33, 651–658 (1968)

    Google Scholar 

  • Rosner, J. L., Kass, L. R., Yarmolinsky, M. B.: Parallel behaviour of F and P1 in causing indirect induction of lysogenic bacteria. Cold Spr. Harb. Symp. quant. Biol. 33, 785–789 (1968)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Institute of Medical Science, The University of Tokyo, P.O. Takanawa, Tokyo, Japan

    Akiko Miura

Authors
  1. Akiko Miura
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Communicated by H. Ozeki

Rights and permissions

Reprints and permissions

About this article

Cite this article

Miura, A. Ultraviolet-induced mutation of bacteriophage λ. Molec. gen. Genet. 134, 21–27 (1974). https://doi.org/10.1007/BF00332809

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00332809

Keywords

Search

Navigation