Summary
An E. coli mutant rpoA109 unable to support the growth of phage P2 produces DNA-dependent RNA polymerase with an altered α subunit. Histidine is substituted for leucine in one tryptic peptide from the mutant α subunit. The existence of only one rpoA gene within the E. coli chromosome is indicated.
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Communicated by H.G. Wittmann
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Fujiki, H., Palm, P., Zillig, W. et al. Identification of a mutation within the structural gene for the a subunit of DNA-dependent RNA polymerase of E. coli . Molec. gen. Genet. 145, 19–22 (1976). https://doi.org/10.1007/BF00331552
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DOI: https://doi.org/10.1007/BF00331552