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Plasmid-determined alterations of Salmonella typhimurium lipopolysaccharides

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Summary

Salmonella typhimurium Rc902 infected with derepressed ColIb mutants gave rise to changes in the composition of bacterial lipopolysaccharides (LPS). Bacteria carrying ColIbdrd7, derepressed in transfer, exhibited a marked decrease in the content of all 0-side-chain sugars of LPS. Similar effects were found upon the introduction of R64-11, also derepressed in transfer. In LPS of S. typhimurium containing ColIbdrd2, derepressed in colicin synthesis, a decrease of abequose content associated with an increase of glucose level was observed. Bacteria carrying the wild-type ColIb, the revertant of a drd mutant to the wild type, or the non colicinogenic strain resulting from the elimination of ColIbdrd2, showed no changes in the sugar composition of LPS.

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Communicated by R. Devoret

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Deryło, M., Głowacka, M., Lorkiewicz, Z. et al. Plasmid-determined alterations of Salmonella typhimurium lipopolysaccharides. Molec. gen. Genet. 140, 175–181 (1975). https://doi.org/10.1007/BF00329785

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