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A study of protective immunity to Amplicaecum robertsi (nematoda) in rats and mice

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Summary

Protective immunity to the larval stages of the nematode, Amplicaecum robertsi was studied in laboratory rodents. A significant (P<0.05) degree of protection was conferred passively to mice by the serum globulins from rats previously infected with eggs of this nematode. Mice vaccinated with excretory-secretory products of 3rd stage larvae collected in vitro were somewhat protected when challenged with A. robertsi eggs but the results were not statistically significant (P>0.05).

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Present address: Department of Community and Preventive Medicine, Stanford University School of Medicine, Stanford, California, U.S.A. 94305. Supported by USPHS Postdoctoral Fellowship Number 1-F2-AI-36,421-01.

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Diconza, J.J. A study of protective immunity to Amplicaecum robertsi (nematoda) in rats and mice. Z. Parasitenk. 41, 65–71 (1973). https://doi.org/10.1007/BF00329631

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  • DOI: https://doi.org/10.1007/BF00329631

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