Abstract
TE146 is a transposing element (TE) consisting of six polytene chromosome bands that has inserted into the no-ocelli (noc 2∶50) locus. This member of Ising's TE family carries two copies of the white and roughest loci. TE146 is lost from noc with a spontaneous frequency of approximately 1 in 22000 chromosomes. All spontaneous losses are accompanied by the reversion of the noc mutation associated with the TE. The TE is associated with fold-back (FB) sequences. The losses of TE146 retain fold-back homology at noc. Of 26 γ-ray-induced losses of TE146, 16 are gross deletions, removing loci neighboring noc and ten are not. The non-deleted γ-ray-induced losses are either noc − and rst + or noc + and rst −. The white+ genes of TE146 are dosage compensated since w/Y; TE146/+ and w/w; TE146/+ flies are sexually dimorphic for eye color. These w + genes are also suppressed by zeste since z w; TE146/+ flies have zeste-colored eyes.
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Gubb, D., Roote, J., Harrington, G. et al. A preliminary genetic analysis of TE146, a very large transposing element of Drosophila melanogaster . Chromosoma 92, 116–123 (1985). https://doi.org/10.1007/BF00328463
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DOI: https://doi.org/10.1007/BF00328463