Summary
Scintigraphy with 99mTc-pertechnetate made it possible to detect focal brain lesions in 4 patients with primary malignant lymphomas of the brain, one patient with CNS involvement with lymphatic immunoblastoma, one patient with Sézary syndrome (mycosis fungoides and T cell leukemia) and one child with a space occupying infiltration of myeloblastic leukemia. The scintigraphic results were verified by morphological data from biopsy or autopsy.
Résumé
Dans quatre cas de lymphome malin et dans un cas de leucémie myéloblastique, les auteurs ont observé des foyers cérébraux. Les localisations sont vérifiées tant par biopsie que par autopsie.
Zusammenfassung
Gehirnszintigraphie mit 99mTc-Pertechnetat ergab bei 4 Patienten mit primären malignen Lymphomen des Gehirns, einem Patienten mit zerebraler Mitbeteiligung des Gehirns bei primärem Lymphknoten-Immunoblastom, einem Patienten mit Sézary-Syndrom (Mycosis fungoides und T-Zellen Leukämie) und einem Kind mit raumforderndem Infiltrat bei myeloblastischer Leukämie herdförmige pathologische Speicherungen. Diese Befunde wurden bioptisch oder autoptisch verifiziert und makroskopisch und histologisch belegt.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Ascari, E., Mussini, C., Ferrari, G.: Sulle localizzazioni endocraniche del linfogranuloma maligno. Minerva Med. 59, 3083–3091 (1968)
Currie, S., Jardine, G.W.H.: Intracranial Hodgkin's disease shown by radioisotope scan. J. Neurol. Neurosurg. Psychiat. 32, 313–316 (1969)
Ebels, E.J.: Reticulosarcomas of the brain presenting as butterfly tumors. Europ. Neurol. 8, 333–338 (1972)
Fisher, D., Mantell, B.S., Urich, H.: The clinical diagnosis and treatment of microgliomatosis: report of a case. J. Neurol. Neurosurg. Psychiat. 32, 474–478 (1969)
Gerstenbrand, F., Jellinger, K., Lutz, D., Maida, E.: Zerebrale Beteiligung bei Sézary-Syndrom. J. Neurol. (in press)
Gérard-Marchant, R., Hamlin, I., Lennert, K., Rilke, R., Stansfeld, A.G., Van Unnik, J.A.M.: Classification of non-Hodgkin's lymphomas. Lancet 1974 II, 406–408
Hubert, J.W.A.: Tumours of the reticuloendothelial system. In: P.J. Vinken and G.W. Bruyn (Eds.). Handbook of Clinical Neurology, vol. 18, 233–267 Amsterdam: North Holland 1975
Jänisch, W., Gerlach, H., Remus, I.: Neoplastic involvement of the CNS in generalized lymphomas. Acta neuropath. (Berl.), Suppl. VI, 81–84 (1975)
Jellinger, K., Radaszkiewicz, Th.: Befall des Nervensystems bei malignen Lymphomen. Tagg. Dtsch.-Österr. Ges. Hämatologie, Bad Nauheim, 29.9.–1. 10. 1975 (abst.) Blut 28 (1975)
Jellinger, K., Radaszkiewicz, Th., Slowik, F.: Primary malignant lymphomas of the central nervous system in man. Acta neuropath. (Berl.) Suppl. VI, 95–102 (1975)
Jones, A.E., Frankel, R.S., DiChiro, G., Johnston, G.S.: Brain scintigraphy with 99mTc pertechnetate, 99mTc polyphosphate, and 67Ga citrate. Radiology 112, 123–129 (1974)
Lennert, K.: Morphology and classification for malignant lymphomas and so-called reticuloses. Acta neuropath. (Berl.) Suppl. VI, 1–16 (1975)
Lukes, R.J., Collins, R.D.: Immunologic characterization of human malignant lymphomas. Cancer 34, 1488–1503 (1974)
Möbius, W., C. Stang-Voss, H.H. Henneukeuser: Light and electron microscopic studies in hemoblastosis with CNS disorder. Acta neuropath. (Berl.) Suppl. VI, 193–198 (1975)
Penning, L., Front, D.: Brain Scintigraphy. Amsterdam. Excerpta Medica 1975
Pochedly, C.: Neurologic manifestations in acute leukemia. New York State J. Med. 75, 575–580, 715–721, 878–882 (1975)
Price, R.A., Johnson, W.W.: The central nervous system in childhood leukemia. I. The arachnoid. Cancer 31, 520–533 (1973)
Rawlinson, D.G., Billingham, M.E., Berry, P.F., Kempson, R.L.: Cytology of the cerebrospinal fluid in patients with Hodgkin's disease and malignant lymphoma. Acta neuropath. (Berl.) Suppl. VI, 187–191 (1975)
Schaumburg, H.H., Plank, C.R., Adams, R.D.: The reticulum cell sarcoma-microglioma group of brain tumours. Brain 95, 199–212 (1972)
Thompson, R.W., DeNardo, G.L.: Therapeutic response of intracranial Hodgkin's disease documented by brain scanning. Cancer 24, 981–984 (1969)
Thompson, R.W., De Nardo, G.L., Kottra, J.S.: The diagnostic value of brain scanning in intracranial lymphomas. Radiology 102, 111–116 (1972)
Zimmerman, H. M.: Malignant lymphomas of the nervous system. Acta neuropath. (Berl.), Suppl. VI, 69–74 (1975)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Heiss, W.D., Jellinger, K. & Podreka, I. Scintigraphy in lymphomas and leukemia of the brain. Neuroradiology 10, 251–255 (1976). https://doi.org/10.1007/BF00327573
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00327573