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Fluorimetric determination of tetracycline and anhydrotetracycline

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Summary

A rapid fluorimetric method employing the complexes of Al3+ with tetracycline (TC) and anhydrotetracycline (ATC) has been used for the measurement of the concentrations of TC and ATC in about 10−7–10−6 mol/l. The assay offers simplicity and rapidly compared with other methods. The recoveries in the determination of synthetic samples are in the range of 95–103% for TC and 101–120% for ATC. Several determinations of TC and ATC in serum and urine have been carried out with satisfactory results.

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Authors and Affiliations

  1. Department of Chemistry, Peking University, 100871, Beijing, PR China

    Wen-Bao Chang, Yi-Bing Zhao & Yun-Xiang Ci

  2. Department of Chemistry, Capital Institute of Medicine, 100054, Beijing, PR China

    Lin-Yun Hu

Authors
  1. Wen-Bao Chang
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  2. Yi-Bing Zhao
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  3. Yun-Xiang Ci
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  4. Lin-Yun Hu
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Chang, WB., Zhao, YB., Ci, YX. et al. Fluorimetric determination of tetracycline and anhydrotetracycline. Fresenius J Anal Chem 344, 128–130 (1992). https://doi.org/10.1007/BF00325128

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  • DOI: https://doi.org/10.1007/BF00325128

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