Summary
A case report of a patient with myelosarcomatosis of the skin six months preceding leukemic generalization of acute myelomonocytic leukemia is presented. To the best of our knowledge this is the first case of a myelosarcoma with generalized skin involvement diagnosed before development of an overt myeloproliferative disease.
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References
Brugo EA, Marshall RB, Riberi AM, Pautasso OE. Preleukemic granulocytic sarcomas of the gastrointestinal tract. Am J Clin Pathol 68, 616–621, 1977
Cheson BD, Christiansen RM (1980) Cutis verticis gyrata: Unusual chloromatous disease in acute myelogenous leukemia. Am J Hematol 8: 415–418
Cohen PR, Rapini RP, Beran M (1987) Infiltrated blue-gray plaques in a patient with leukemia. Arch Dermatol 123: 251–254
Comings DE, Fayen AW, Carter P (1965) Myeloblastoma preceding blood and marrow evidence of acute leukemia. Cancer 18: 253–258
Ersboll J, Petri J, Jensen KH, Hansen MM (1980) Granulocytic sarcoma preceding acute myeloid leukemia. Scand J Haematol 24: 435–445
Horny H-P, Parwaresch MR, Kaiserling E, Müller K, Olberman M, Mainzer K, Lennert K (1986) Mast cell sarcoma of the larynx. J Clin Pathol 39: 596–602
Horny H-P, Kaiserling E (1988) Lymphoid cells and tissue mast cells of bone marrow lesions in systemic mastocytosis: a histological and immunohistological study. Br J Haematol 69: 449–455
Horny H-P, Engst U, Walz RS, Kaiserling E (1989) In situ immunophenotyping of lymphocytes in human bone marrow. An immunohistochemical study. Br J Haematol (in press)
Krause, JR (1979) Granulocyticsarcoma preceding acute leukemia. Cancer 4: 1017–1021
Leder, LD (1964) Über die selektive fermentzytochemische Darstellung von neutrophilen myeloischen Zellen und Gewebsmastzellen im Paraffinschnitt. Klin Wochenschr 42: 553
Long JC, Mihm MC (1977) Multiple granulocytic tumors of the skin. Cancer 39: 2004–2016
Mason TE, Demarree RS, Margolis CI (1973) Granulocytic sarcoma. Two years preceding myelogenous leukemia. Cancer 31: 423–432
Meis JM, Butler JJ, Osborne BM, Manning JT (1986) Granulocytic sarcoma in nonleukemic patients. Cancer 58: 2697–2709
Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE, Bennett JM (1981) Granulocytic sarcoma: A clinicopathologic study of 61 biopsied cases. Cancer 48: 1426–1437
Sun NCJ, Ellis R (1980) Granulocytic sarcoma of the skin. Arch Dermatol 116: 800–802
Pfeiffer J, Oehmichen M, Benöhr H-Chr, Frommhold W, Rückle H, Waller HD, Wilmans W, Wilms Kl (1974) Meningiosis leucaemica bei chlorom mit später leukämischer Generalisation. Dtsch Med Wochenschr 99: 242–245
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Muller, C.P., Ziegler, A., Steinke, B. et al. Myelosarcomatosis of the skin preceding leukemic generalization of acute myelomonocytic leukemia. Blut 58, 165–167 (1989). https://doi.org/10.1007/BF00320439
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DOI: https://doi.org/10.1007/BF00320439