Summary
A combination of immunocytochemical and biochemical methods was used to study histamine in the turtle retina. Histamine-like immunoreactivity was localized within paraboloids of certain cone photoreceptors by use of two different antisera directed against histamine. Preincubation of eyecups in Ringer's containing 10 μM histamine selectively increased the immunoreactivity of these photoreceptor paraboloids. The present localization of histamine in paraboloids indicated that, although histamine is in photoreceptors of the turtle retina, it may play some metabolic or neuromodulatory role, and not function as a neurotransmitter.
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Eldred, W.D., Schütte, M., Cochrane, D.E. et al. Immunocytochemical and biochemical studies of histamine in the retina of the turtle Pseudemys scripta . Cell Tissue Res 267, 449–454 (1992). https://doi.org/10.1007/BF00319367
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DOI: https://doi.org/10.1007/BF00319367