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Early cytological differentiation in the cerebral hemisphere of mice

An electronmicroscopical study

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Zeitschrift für Zellforschung und Mikroskopische Anatomie Aims and scope Submit manuscript

Summary

1. The parietal region of the telencephalic vesicle of mice embryos and newborn mice has been studied electronmicroscopically. Special attention has been paid to developing glia cells. 2. In early stages it is impossible to differentiate neuroblasts from glioblasts. 3. Late pre-natal stages allow a recognition of glioblasts on account of their ultrastructure, as the overall structure of the nucleus and the cytoplasm of a glioblast has a greater electron-density than that of a neuroblast. 4. Glioblasts have a lobulated nucleus at this stage (20th day i.u.) while neuroblasts possess an ovoid nucleus. The quantity of endoplasmic reticulum and of the number of ribosomes is relatively greater in neuroblasts than in glioblasts.

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We gratefully acknowledge the support of the Deutsche Forschungsgemeinschaft (Gl. 28/4) and Stiftung Volkswagenwerk.

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Meller, K., Breipohl, W. & Glees, P. Early cytological differentiation in the cerebral hemisphere of mice. Zeitschrift für Zellforschung 72, 525–533 (1966). https://doi.org/10.1007/BF00319257

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  • DOI: https://doi.org/10.1007/BF00319257

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