Abstract
Rabbits were poisoned with carbon tetrachloride. After 12 hours, the body temperature of the animals was lowered and maintained at 31–32°C. for the next 12 hours by the surface-immersion technique. Liver function, as estimated by the time of appearence of BSP in bile, was found close to normal. This protective effect of hypothermia is probably due to the lowered basic metabolic rate.
Zusammenfassung
Kaninchen, die 12 Std nach Tetrachlorkohlenstoffvergiftung weitere 12 Std durch Oberflächen-Immersionstechnik bei 31–32°C unterkühlt wurden, zeigten bei der Zeitbestimmung des Ausscheidungsbeginns des Bromsulphophthaleins (BSP) in der Galle ein annähernd normales Verhalten der Leberfunktion. Die Schutzwirkung der Hypothermie beruht anscheinend auf der Herabsetzung des Stoffwechsels.
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Bartsokas, S., Papadimitriou, D.G. & Varonos, D. Die Schutzwirkung der Hypothermie auf die Leberfunktion bei der Tetrachlorkohlenstoffvergiftung des Kaninchens. Arch Toxicol 29, 67–72 (1972). https://doi.org/10.1007/BF00316516
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DOI: https://doi.org/10.1007/BF00316516