Abstract
Acrylamide administration to rats caused clear alteration of blood thiamine content, which appeared to reflect suppressed intake and/or utilization of the vitamin in the body. Decreased utilization of thiamine does not seem to be induced by decreased binding of thiamine pyrophosphate (TPP) and apotransketolase, because acrylamide did not affect the K m of TPP for transketolase activity.
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Igisu, H., Goto, I. Acrylamide and thiamine. Arch Toxicol 63, 248–249 (1989). https://doi.org/10.1007/BF00316377
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DOI: https://doi.org/10.1007/BF00316377