Abstract
Extracorporeal hemodialyses were carried out in a female patient with severe diquat intoxication. Diquat clearance was on average 3.17 ml/min. Only 0.84 mg diquat could be eliminated from the blood serum by 11.5 hrs of dialysis. Hemodialysis is therefore not an efficient technique for removing amounts of diquat from the organism that are toxicologically relevant one day after ingestion.
Zusammenfassung
Bei einer Patientin mit schwerer Diquat-Intoxikation wurden extrakorporale Hämodialysen durchgeführt. Die Diquat-Clearance betrug im Mittel 3,17 ml/min. Durch 11,5stündige Dialyse konnten nur 0,84 mg Diquat aus dem Blutserum eliminiert werden. Die Hämodialyse ist daher kein geeignetes Verfahren, um einen Tag nach der Ingestion toxikologisch relevante Mengen Diquat aus dem Organismus zu entfernen.
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The analytical assistance of Mr. S. Schwind is gratefully acknowledged.
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Okonek, S., Hofmann, A. On the question of extracorporeal hemodialysis in diquat intoxication. Arch Toxicol 33, 251–257 (1975). https://doi.org/10.1007/BF00311277
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DOI: https://doi.org/10.1007/BF00311277