Abstract
This report describes the modifications necessary to adapt the pH stat and a Δ pH method for the estimation of acetylcholinesterase activity in the erythrocytes of various species of laboratory animals. Both methods were evaluated in studies in which cholinesterase inhibitors, carbamates and Organophosphorus compounds, were given to the animals.
Zusammenfassung
Dieser Bericht beschreibt die Modifikationen, die zur Anpassung der pH Stat und einer Δ pH-Methode für die Bestimmung der Acetylcholinesteraseaktivität in den Erythrocyten verschiedener Laboratoriumstierarten notwendig sind. Beide Methoden werden für Untersuchungen eingesetzt, bei denen den Tieren Cholinesteraseinhibitoren, Carbamate und Organophosphate, verabreicht worden waren.
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Pickering, R.G., Pickering, C.E. Methods for the estimation of acetylcholinesterase activity in the erythrocytes of laboratory animals given carbamates or organophosphorus compounds. Arch. Toxicol. 31, 197–216 (1974). https://doi.org/10.1007/BF00311053
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DOI: https://doi.org/10.1007/BF00311053