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Enzyme histochemistry of the choroid plexus in rat and squirrel monkey

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Summary

The reactions given for various oxidative and hydrolytic enzymes by the choroid plexus of the squirrel monkey and the rat brain have been studied in detail. The lining cells show strong activity for citric acid cycle and glycolytic pathways enzymes. The stroma shows strong activity for adenosine triphosphatase, alkaline phosphatase, adenosine monophosphatase and glucose-6-phosphatase. The peripheral part or luminal borders of the cytoplasm of the choroidal cells show strong activity for alkaline phosphatase, adenosine monophosphatase and adenosine triphosphatase, and a well developed thiamine pyrophosphatase positive Golgi complex, indicating their participation in the formation and transport of secretory material. The nucleoli of the lining cells give a positive reaction for glucose-6-phosphatase and adenosine triphosphatase. Acid phosphatase like the thiamine pyrophosphatase positive Golgi material is found all over the cytoplasm. The functional significance of these findings is briefly discussed.

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Authors and Affiliations

  1. Yerkes Regional Primate Research Center, Emory University, 30322, Atlanta, Georgia

    Totada R. Shantha & Sohan L. Manocha

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  1. Totada R. Shantha
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  2. Sohan L. Manocha
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Additional information

This work has been carried out with the aid of Grant No. FR-00165 from the Animal Resources Branch, National Institutes of Health and NASA Grant NGR-11-001-016.

T. R. Shanthaveerappa in previous publications.

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Shantha, T.R., Manocha, S.L. Enzyme histochemistry of the choroid plexus in rat and squirrel monkey. Histochemie 14, 149–160 (1968). https://doi.org/10.1007/BF00306337

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  • DOI: https://doi.org/10.1007/BF00306337

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