Summary
A spontaneous abortion with an unbalanced translocation involving chromosomes 3, 4 and 14 is described. The mother and grandmother of the abortus were balanced carriers of the condition. A marker 9 was also segregating in the family.
References
Allderdice, P. W., Miller, O. J., Miller, D. A., Breg, W. R., Gendel, E., Zelson, C.: Familial translocation involving chromosomes 6, 14 and 20, identified by quinacrine fluorescence. Humangenetik 13, 205–209 (1971)
Arrighi, F. E., Hsu, T. C.: Localization of heterochromatin in human chromosomes. Cytogenetics 10, 81–86 (1971)
Fredga, K., Hall, B.: A complex familial translocation involving chromosomes 5, 9 and 13.. Cytogenetics 9, 294–306 (1970)
Hamerton, J. L.: Human Cytogenetics, Vol. 1, General Cytogenetics. New York-London: Academic Press 1971
Jacobs, P. A.: The inheritance of randomyly ascertained chromosome abnormalities in human population cytogenetics, P. A. Jacobs, D. H. Price, and P. Law, Eds., pp. 90–102. Edinburgh: University Press 1970
Jacobs, P. A., Buckton, K. E., Cunningham, C., Newton, M.: An analysis of the break points of structural rearrangements in man. J. med. Genet. 11, 65–68 (1974)
Nuzzo, F., Marini, A., Baglioni, C., Ford, C. E., de Carli, L., Sereni, L. P.: A case of multiple chromosomal rearrangements with persistence of fetal haemoglobin. Cytogenetics 7, 169–182 (1968)
Paris Conference (1971): Standardization in human cytogenetics. Birth Defects: Original Article Series VIII, 7 (1972). The National Foundation, New York
Sanchez, O., Junis, J. J., Escobar, J. I.: Partial 11 trisomy in a child resulting from a complex maternal rearrangement of chromosomes 11, 12 and 13. Humangenetik 22, 59–65 (1974)
Seabright, M.: A rapid banding technique for human chromosomes. Lancet 1971 II, 971–972
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Creasy, M.R., Crolla, J.A. & Daker, M.G. A familial reciprocal translocation between three chromosomes. Hum Genet 24, 303–308 (1974). https://doi.org/10.1007/BF00297594
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DOI: https://doi.org/10.1007/BF00297594