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Gene frequencies of red cell adenosine deaminase, adenylate kinase, phosphoglucomutase, acid phosphatase and serum α1-antitrypsin (Pi) in a German population

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Summary

Frequencies and phenotype distribution of red cell adenosine deaminase (ADA), adenylate kinase (AK), phosphoglucomutase (PGM1), acid phosphatase (AP) and serum α1-antitrypsin (α1-at or Pi) were examined in a German group of the area of Hamburg. The observed distribution of phenotypes in all five systems is consistent with that expected by the Hardy-Weinberg equilibrium. Within the mother/child combinations we found no incompatible combination. The results of additional family investigations for α1-antitrypsin are consistent with Mendelian expectation.

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Authors and Affiliations

  1. Institute of Human Genetics, University of Hamburg, Germany

    H. Werner Goedde, Heide-G. Benkmann, Ingeborg Christ, Surjit Singh & Ludwig Hirth

Authors
  1. H. Werner Goedde
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  2. Heide-G. Benkmann
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  3. Ingeborg Christ
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  4. Surjit Singh
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  5. Ludwig Hirth
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Goedde, H.W., Benkmann, HG., Christ, I. et al. Gene frequencies of red cell adenosine deaminase, adenylate kinase, phosphoglucomutase, acid phosphatase and serum α1-antitrypsin (Pi) in a German population. Hum Genet 10, 235–243 (1970). https://doi.org/10.1007/BF00295786

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  • DOI: https://doi.org/10.1007/BF00295786

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