Abstract
Root tip mitosis in both Vinca rosea and the chosen control Lepidium sativum is susceptible to the effects of colchicine at and above 5×10−4 M. — Root tip mitosis in L. sativum is susceptible to the effects of vinblastine at concentrations equal to and greater than 10−4 M, while root tip mitosis in V. rosea, the plant which is the source of vinblastine, is unaffected by exogenously-applied VBL at concentrations up to and including 10−2 M. — The possible mechanisms by which this resistance of V. rosea to vinblastine might be conferred are discussed.
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Kramers, M.R., Stebbings, H. The insensitivity of Vinca rosea to vinblastine. Chromosoma 61, 277–287 (1977). https://doi.org/10.1007/BF00292811
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DOI: https://doi.org/10.1007/BF00292811