Abstract
A DNA sequence of the lampbrush loops nooses from the Y chromosome of Drosophila hydei (designated MY3) is described which is composed of a Y-specific sequence region homologous to the ay1 DNA sequence family described earlier and a sequence region without homology to ay1 but with homology to DNA sequences in autosomal and X chromosomal locations. The sequence region homologous to ay1 contains five tandem repeats. Since these repeats display distinct differences, their evolutionary history can be derived and it can be demonstrated that they originated from repeated successive duplications. Based on the structural properties of the MY3 DNA sequence, we propose a model for the molecular structure of the lampbrush loop nooses, which may be a general model for Y chromosomal lampbrush loops. The model postulates a “frame” function for the Y-specific repeat clusters of the Y chromosomal lampbrush loops. Into these clusters other sequences are inserted, probably by transposition. The implications of this model and the possible functions of the Y chromosomal lampbrush loops are discussed.
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Vogt, P., Hennig, W. Molecular structure of the lampbrush loops nooses of the Y chromosome of Drosophila hydei . Chromosoma 94, 459–467 (1986). https://doi.org/10.1007/BF00292755
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DOI: https://doi.org/10.1007/BF00292755