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The densitometric study of G bands on human metaphase chromosomes

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Summary

The method of densitometric measurement of G bands on human metaphase chromosomes is described, and some factors influencing the densitometric patterns are discussed. The densitometric patterns are reproducible and typical for a given chromosomal pair, although they display some degree of variability. Typical patterns of all human metaphase chromosomes are presented, with the patterns obtained from the measurement of some structurally abnormal chromosomes (t13q14q, t14q21q, Xp-).

Zusammenfassung

Wir beschreiben die Methode der photometrischen Darstellung von G-Banden an menschlichen Chromosomen und diskutieren über einigen Faktoren, die das Resultat beeinflussen. Die photometrischen Kurven sind reproduzierbar und für jedes Chromosomenpaar typisch. Selbstverständlich muß man mit geringen Abstufungen ihrer Variabilität rechnen. Wir zeigen unsere typischen Kurven aller menschlichen Chromosomen, die mit Hilfe der ASG-Technik gefärbt wurden. Gleichzeitig geben wir einige Kurven abnormaler Chromosomen wieder, die auch in unserem Labordargestellt wurden (t(13q14q), t(14q21q), Xp-).

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Authors and Affiliations

  1. Third Medical Department, Charles University, Prague

    Radovan Chrz, Jan Kozák & Jana Málková

  2. Geophysical Institute of the Czechoslovakian Academy of Sciences, Prague

    Radovan Chrz, Jan Kozák & Jana Málková

  3. Cytogenetical Laboratory, III Medical Department, U nemocnice 1, Praha 2, Czechoslovakia

    Radovan Chrz

Authors
  1. Radovan Chrz
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  2. Jan Kozák
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  3. Jana Málková
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Chrz, R., Kozák, J. & Málková, J. The densitometric study of G bands on human metaphase chromosomes. Humangenetik 18, 149–154 (1973). https://doi.org/10.1007/BF00291482

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  • DOI: https://doi.org/10.1007/BF00291482

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