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Nucleoli of cultured human lymphocytes

II. Nucleolar fusion and its relation to acrocentric association

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Summary

Nucleolar fusion and nucleolus formation occurred simultaneously, immediately after mitosis, in cultured human lymphocytes. Evidence is presented that in late telophase and post-telophase, the individual nucleolar organising site includes two components, represented in post-telophase by the nucleolus and its attached process; that fusion can be either directly between the nucleoli or via the processes; and that the latter type of fusion persists into metaphase as acrocentric associations, whilst the former is lost.

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Gani, R. Nucleoli of cultured human lymphocytes. Hum Genet 42, 271–282 (1978). https://doi.org/10.1007/BF00291307

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