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The fine structure of human chromosomes isolated by shearing-sieving

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Abstract

Chromosomes isolated by the new technique of shearing-sieving, even if unstained, show a less degraded organisation than those prepared for the electron microscope by other techniques. The chromosomes are banded, may show more bands if stretched, and the centromere is a precisely defined structure. Appearances resulting from this technique are compared with those from other techniques.

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Skaer, R.J., Whytock, S. The fine structure of human chromosomes isolated by shearing-sieving. Chromosoma 55, 85–90 (1976). https://doi.org/10.1007/BF00288331

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  • DOI: https://doi.org/10.1007/BF00288331

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